Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 4/20 | 0.58 |
| ▸ | IP6K3 | Q96PC2 | 4/20 | 0.58 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928538 | 0.85 | PTGS1 (0.54) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL4339483 | 0.85 | NR4A1 (0.44) | IP6K1IP6K3IP6K2ALDH1A1L3MBTL1 | |
| SCHEMBL3711076 | 0.85 | PRNP (0.45) | IP6K1IP6K3IP6K2ALDH1A1HTT | |
| SCHEMBL4035250 | 0.84 | HTT (0.57) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL19119250 | 0.84 | PTGS1 (0.53) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL4333981 | 0.83 | ALDH1A1 (0.58) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL13508 | 0.83 | PTGS1 (0.51) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL11375484 | 0.82 | IP6K1 (0.58) | IP6K1IP6K3IP6K2ALDH1A1HTT | |
| SCHEMBL15280716 | 0.81 | RAB9A (0.52) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL14789796 | 0.80 | RAB9A (0.51) | IP6K1IP6K3IP6K2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-6964975-B2 | Isoxazole and thiazole compounds and use thereof as medicine | KIRIN BEER KABUSHIKI KAISHA (JP) | 2005-11-15 | — | — | US | disclosed |
| US-20030114505-A1 | Novel isoxazole and thiazole compounds and use thereof as drugs | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1258484-A1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114505-A1 | Novel isoxazole and thiazole compounds and use thereof as drugs | LPAR3, LPAR1, LPAR4 | IP6K1 435/4885IP6K3 323/4885IP6K2 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.