Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4034617 | 1.00 | QPCT (0.44) | QPCTSMN1; SMN2HTTMAPTUSP2 | |
| SCHEMBL4034972 | 0.96 | QPCT (0.47) | QPCTSMN1; SMN2HTTMAPTUSP2 | |
| SCHEMBL4032554 | 0.96 | QPCT (0.47) | QPCTSMN1; SMN2HTTMAPTUSP2 | |
| Trifluoroacetic Acid SCHEMBL4034917 | 0.85 | QPCT (0.49) | QPCTSMN1; SMN2HTTMAPTUSP2 | |
| SCHEMBL4034774 | 0.79 | GAA (0.52) | SMN1; SMN2MAPTLMNAGAATSHR | |
| SCHEMBL6186742 | 0.78 | QPCT (0.46) | QPCTSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL4035027 | 0.70 | L3MBTL1 (0.47) | SMN1; SMN2HTTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL4209294 | 0.68 | QPCT (0.42) | QPCTHTTMAPTUSP2GAA | |
| SCHEMBL4033362 | 0.68 | GAA (0.53) | MAPTLMNAGAATSHRMAPK1 | |
| Trifluoroacetic Acid SCHEMBL4033431 | 0.67 | QPCT (0.45) | QPCTSMN1; SMN2HTTMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |