Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4217064 | 0.85 | FABP1 (0.42) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4212852 | 0.82 | FABP1 (0.45) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4208499 | 0.82 | GAA (0.47) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4208204 | 0.82 | ALDH1A1 (0.44) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4214876 | 0.82 | FABP1 (0.40) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4220008 | 0.76 | ALDH1A1 (0.40) | FABP1GAAALDH1A1MAPK1MAPT | |
| SCHEMBL4038496 | 0.74 | PSEN1 (0.39) | ALDH1A1KMT2AHTT | |
| SCHEMBL4032554 | 0.71 | QPCT (0.47) | QPCTFABP1GAAALDH1A1MAPT | |
| SCHEMBL4034972 | 0.71 | QPCT (0.47) | QPCTFABP1GAAALDH1A1MAPT | |
| SCHEMBL4037792 | 0.71 | ALDH1A1 (0.37) | GAAALDH1A1PKMTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404690-B2 | Piperazine-2-carboxamide derivatives | MERCK SERONO SA (CH) | 2013-03-26 | — | — | US | claimed |
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |