Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032554 | 1.00 | QPCT (0.47) | QPCTL3MBTL1KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL4032508 | 0.96 | QPCT (0.44) | QPCTL3MBTL1KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL4034617 | 0.96 | QPCT (0.44) | QPCTL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL4034774 | 0.82 | GAA (0.52) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL6186742 | 0.81 | QPCT (0.46) | QPCTL3MBTL1KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL4034917 | 0.80 | QPCT (0.49) | QPCTL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL4035027 | 0.73 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL4209294 | 0.71 | QPCT (0.42) | QPCTALDH1A1GAAPOLBMAPT | |
| SCHEMBL4034935 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL4033362 | 0.69 | GAA (0.53) | L3MBTL1ALDH1A1HPGDGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404690-B2 | Piperazine-2-carboxamide derivatives | MERCK SERONO SA (CH) | 2013-03-26 | — | — | US | claimed |
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |