Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037282 | 0.85 | MAPT (0.52) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL4029460 | 0.83 | NPSR1 (0.61) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL9903838 | 0.82 | NPSR1 (0.48) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL4028725 | 0.82 | MAPT (0.49) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL8477483 | 0.79 | ALDH1A1 (0.53) | NPSR1ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL9903324 | 0.79 | NPSR1 (0.44) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL9903605 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL4030815 | 0.78 | KMT2A (0.54) | NPSR1ALDH1A1NTRK1MAPTTSHR | |
| SCHEMBL4036524 | 0.76 | NTRK1 (0.56) | NPSR1NTRK1MAPTKMT2AMEN1 | |
| SCHEMBL4029125 | 0.75 | LPAR1 (0.60) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |