Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527223 | 0.89 | MEN1 (0.61) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL4037282 | 0.89 | MAPT (0.52) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL17790727 | 0.88 | MAPT (0.60) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL4028725 | 0.86 | MAPT (0.49) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL9903838 | 0.86 | NPSR1 (0.48) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL4032643 | 0.84 | TSHR (0.51) | NPSR1TSHRHTTMAPTGAA | |
| SCHEMBL4034243 | 0.84 | KMT2A (0.49) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL4032659 | 0.83 | NPSR1 (0.52) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL5530438 | 0.83 | MEN1 (0.54) | NPSR1TSHRHTTMAPTMEN1 | |
| SCHEMBL4030815 | 0.81 | KMT2A (0.54) | NPSR1TSHRHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |