SCHEMBL403268

SCHEMBL403268

CC(=O)NC1COC(COS(=O)(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 3/20 0.33
▸ BDNF P23560 3/20 0.32
▸ PTN P21246 2/20 0.32
▸ MDK P21741 2/20 0.32
▸ IARS1 P41252 3/20 0.32
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ CD69 Q07108 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6123871 0.89 OGA (0.32) OGABDNFPTNMDK
SCHEMBL30980651 0.82 OGA (0.36) OGAIARS1
SCHEMBL16250370 0.81 OGA (0.36) OGA
SCHEMBL12355191 0.81 IARS1 (0.33) IARS1
SCHEMBL14478983 0.81 IARS1 (0.33) IARS1
SCHEMBL9976875 0.81 IARS1 (0.33) IARS1
SCHEMBL25499753 0.79 ALDH1A1 (0.35) OGACD69
SCHEMBL23705039 0.77 OGA (0.46) OGACD69
SCHEMBL24916748 0.77 OGA (0.39) OGACYP2C9CYP2C19
SCHEMBL12178004 0.77 OGA (0.46) OGACD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF SANOFI-AVENTIS (FR) 2012-03-15 — — US disclosed
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof SANOFI-AVENTIS (FR) 2007-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF HPSE, HAAO, HEXD OGA 76/4885BDNF 1751/4885PTN 3287/4885
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof HPSE, HAAO, HEXD OGA 68/4885BDNF 1731/4885PTN 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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