SCHEMBL9976875

SCHEMBL9976875

O=S(=O)(O)NC1COC(COS(=O)(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IARS1 P41252 4/20 0.33
▸ F10 P00742 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14478983 1.00 IARS1 (0.33) IARS1F10
SCHEMBL12355191 1.00 IARS1 (0.33) IARS1F10
SCHEMBL6123884 0.87 F10 (0.30) IARS1F10
SCHEMBL13692694 0.87 F10 (0.30) F10
SCHEMBL12346246 0.86 F10 (0.35) F10
SCHEMBL730705 0.85 F10 (0.35) IARS1F10
SCHEMBL12892710 0.85 F10 (0.35) IARS1F10
SCHEMBL12895304 0.85 F10 (0.35) IARS1F10
SCHEMBL403268 0.81 OGA (0.33) IARS1
SCHEMBL14478994 0.80 IARS1 (0.33) IARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355658-A1 MEDICAL USE OF TAFOXIPARIN DILAFOR AB (SE) 2023-11-09 — — US disclosed
US-20230144378-A1 TAFOXIPARIN FOR THE TREATMENT OF PREECLAMPSIA DILAFOR AB (SE) 2023-05-11 — — US disclosed
US-10023659-B2 Processes for the production of chemically-modified heparins DILAFOR AB (SE) 2018-07-17 — — US disclosed
US-10023603-B2 Preparation of monosaccharides, disaccharides, trisaccharides, and pentasaccharides of heparinoids FORMOSA LABORATORIES, INC. (TW) 2018-07-17 — — US disclosed
US-20170015695-A1 PREPARATION OF MONOSACCHARIDES, DISACCHARIDES, TRISACCHARIDES, AND PENTASACCHARIDES OF HEPARINOIDS FORMOSA LABORATORIES, INC. (TW) 2017-01-19 — — US disclosed
US-9480701-B2 Low anticoagulant heparins DILAFORETTE AB (SE) 2016-11-01 — — US disclosed
US-9480702-B2 Use of chemically modified heparin derivates in sickle cell disease DILAFORETTE AB (SE) 2016-11-01 — — US disclosed
US-9475888-B2 Non anti-coagulative glycosaminoglycans comprising repeating disaccharide unit and their medical use DILAFOR AB (SE) 2016-10-25 — — US disclosed
US-20160137754-A1 NEW PROCESSES FOR THE PRODUCTION OF CHEMICALLY-MODIFIED HEPARINS DILAFOR AB (SE) 2016-05-19 — — US disclosed
US-9243018-B2 Synthetic heparin pentasaccharides DR. REDDY'S LABORATORIES, SA (CH) 2016-01-26 — — US disclosed
US-20120220759-A1 SYNTHETIC HEPARIN DISACCHARIDES ALCHEMIA LIMITED (AU) 2012-08-30 — — US disclosed
US-20120208993-A1 SYNTHETIC HEPARIN TRISACCHARIDES ALCHEMIA LIMITED (AU) 2012-08-16 — — US disclosed
US-20120156294-A1 Pharmaceutical Compositions of Selective Factor Xa Inhibitors for Oral Administration NOVO NORDISK A/S (DK) 2012-06-21 — — US disclosed
US-8114970-B2 Synthetic heparin monosaccharides ALCHEMIA LIMITED (AU) 2012-02-14 — — US disclosed
US-20110236474-A1 Pharmaceutical Compositions of Selective Factor Xa Inhibitors for Oral Administration NOVO NORDISK A/S (DK) 2011-09-29 — — US disclosed
US-20110201572-A1 PHARMACEUTICAL COMPOSITION WITH GLYCOSAMINOGLYCANS AND USE THEREOF IN THE TREATMENT OF CHRONIC ULCERS LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) 2011-08-18 — — US disclosed
US-20100239673-A1 Blood compatible nanomaterials and methods of making and using the same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-09-23 — — US disclosed
US-7741311-B2 Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing MOUSA SHAKER 2010-06-22 — — US disclosed
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA LIMITED (AU) 2009-07-23 — — US disclosed
US-7541445-B2 Synthetic heparin pentasaccharides ALCHEMIA LIMITED (AU) 2009-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236474-A1 Pharmaceutical Compositions of Selective Factor Xa Inhibitors for Oral Administration F12, F13B, F11 IARS1 4257/4885F10 8/4885
US-20100239673-A1 Blood compatible nanomaterials and methods of making and using the same MB, ICAM1, F3 IARS1 815/4885F10 27/4885
US-10023603-B2 Preparation of monosaccharides, disaccharides, trisaccharides, and pentasaccharides of heparinoids HPSE, DDOST, FUT5 IARS1 2204/4885F10 134/4885
US-10023659-B2 Processes for the production of chemically-modified heparins HPSE, F10, FGB IARS1 2708/4885F10 2/4885
US-20120156294-A1 Pharmaceutical Compositions of Selective Factor Xa Inhibitors for Oral Administration F12, F13B, F11 IARS1 4004/4885F10 8/4885
US-20230355658-A1 MEDICAL USE OF TAFOXIPARIN PGF, PTGIR, PTGFR IARS1 3591/4885F10 35/4885
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES HPSE, DDOST, STT3A IARS1 2572/4885F10 107/4885
US-20170015695-A1 PREPARATION OF MONOSACCHARIDES, DISACCHARIDES, TRISACCHARIDES, AND PENTASACCHARIDES OF HEPARINOIDS HPSE, DDOST, FUT5 IARS1 2204/4885F10 134/4885
US-20120220759-A1 SYNTHETIC HEPARIN DISACCHARIDES HPSE, DDOST, STT3A IARS1 2424/4885F10 144/4885
US-20230144378-A1 TAFOXIPARIN FOR THE TREATMENT OF PREECLAMPSIA PGF, PLAUR, SERPINC1 IARS1 3846/4885F10 29/4885
US-20160137754-A1 NEW PROCESSES FOR THE PRODUCTION OF CHEMICALLY-MODIFIED HEPARINS F10, SERPINC1, HPSE IARS1 2741/4885F10 1/4885
US-20120208993-A1 SYNTHETIC HEPARIN TRISACCHARIDES HPSE, SERPINC1, DDOST IARS1 1785/4885F10 116/4885
US-20110201572-A1 PHARMACEUTICAL COMPOSITION WITH GLYCOSAMINOGLYCANS AND USE THEREOF IN THE TREATMENT OF CHRONIC ULCERS CD44, MATR3, MMP7 IARS1 3058/4885F10 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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