SCHEMBL4032826

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14249127	0.83	PTGS2 (0.34)	ALDH1A1MEN1CYP2C19KMT2ATSHR
	SCHEMBL4036613	0.72	NOTUM (0.44)	ALDH1A1KDM4EMEN1CYP2C19KMT2A
	SCHEMBL8287013	0.71	KDM4E (0.41)	ALDH1A1KDM4EMEN1ALPGCYP2C9
	SCHEMBL27401270	0.70	AVPR1A (0.43)	ALDH1A1MEN1CYP2C9KMT2ATSHR
	SCHEMBL6593121	0.68	AVPR1A (0.53)	ALDH1A1KDM4ECYP2C9CYP2C19TSHR
	SCHEMBL4035995	0.67	IDO1 (0.49)	ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1
	SCHEMBL9039798	0.67	ALDH1A1 (0.41)	ALDH1A1KDM4EMEN1ALPGCYP2C9
	SCHEMBL3830999	0.67	PTGS2 (0.52)	ALDH1A1KDM4EMEN1CYP2C9CYP2C19
	SCHEMBL27567953	0.67	KDM4E (0.40)	ALDH1A1KDM4EMEN1ALPGCYP2C9
	SCHEMBL13080930	0.66	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.