SCHEMBL4035995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14249281	0.89	POLB (0.47)	ALDH1A1MAPTRAB9AHPGDHTT
	SCHEMBL22200913	0.82	TSHR (0.47)	ALDH1A1MAPTRAB9ANPC1CYP2C19
	SCHEMBL8279471	0.77	CYP2C19 (0.33)	ALDH1A1MAPTRAB9AHPGDCYP2C19
	SCHEMBL4036284	0.77	SMN1; SMN2 (0.36)	ALDH1A1MAPTHPGDCYP2C19SMN1; SMN2
	SCHEMBL4036279	0.76	SMN1; SMN2 (0.37)	IDO1ALDH1A1MAPTRAB9AHPGD
	SCHEMBL998243	0.76	IDO1 (0.43)	IDO1RAB9ANPC1CYP2C19SMN1; SMN2
	SCHEMBL31082928	0.76	GAA (0.50)	ALDH1A1MAPTHPGDHTTNPSR1
	SCHEMBL20028264	0.74	ALDH1A1 (0.57)	ALDH1A1MAPTRAB9AHPGDNPC1
	SCHEMBL14249218	0.73	LMNA (0.47)	ALDH1A1MAPTRAB9AHPGDHTT
	SCHEMBL14248904	0.72	POLB (0.46)	ALDH1A1MAPTRAB9AHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.