Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566628 | 0.90 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL11285273 | 0.86 | PPARA (0.53) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL3484028 | 0.84 | FBP1 (0.47) | PPARGPPARA | |
| SCHEMBL4035654 | 0.81 | PPARG (0.48) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL4033438 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL29224676 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL4036197 | 0.78 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL5795204 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL5794671 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10PPARGPPARA | |
| SCHEMBL11738947 | 0.76 | PPARG (0.72) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |