Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286190 | 0.88 | PPARA (0.59) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4685610 | 0.87 | FBP1 (0.53) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4033755 | 0.84 | KDM4E (0.48) | PPARAPPARG | |
| SCHEMBL3484043 | 0.84 | PPARA (0.48) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL3484819 | 0.82 | FBP1 (0.47) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL3484624 | 0.82 | FBP1 (0.51) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL3484747 | 0.80 | PPARA (0.62) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4681650 | 0.80 | FBP1 (0.54) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL5495350 | 0.79 | FBP1 (0.53) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL3900554 | 0.78 | PPARA (0.68) | FBP1PPARAABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | IPO5, PPIP5K2, IPO4 | FBP1 2382/4885PPARA 1045/4885ABCB11 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.