Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484819 | 0.84 | FBP1 (0.47) | PPARGPPARAALDH1A1SLC13A5LMNA | |
| SCHEMBL4037713 | 0.84 | ALDH1A1 (0.54) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL4037829 | 0.83 | PTGDR2 (0.45) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL4033755 | 0.81 | KDM4E (0.48) | PPARGPPARAPPARDALDH1A1KDM4E | |
| SCHEMBL4035649 | 0.78 | PPARA (0.49) | PPARGPPARACYP2C9ALDH1A1KDM4E | |
| SCHEMBL4033331 | 0.78 | PPARA (0.66) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL6446385 | 0.78 | RXRA (0.47) | PPARGPPARAALDH1A1KDM4ESLC13A5 | |
| SCHEMBL6448663 | 0.77 | SLC13A5 (0.39) | PPARGPPARAALDH1A1SLC13A5RXRA | |
| SCHEMBL7795580 | 0.77 | PTGS2 (0.48) | CYP2C9ALDH1A1KDM4EHSD17B10SLC13A5 | |
| SCHEMBL4034269 | 0.76 | LTB4R (0.48) | PPARAPPARDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |