Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 7/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489951 | 0.73 | KDM4E (0.37) | PRKDCKDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL297319 | 0.71 | MEN1 (0.54) | TNKSKDM4ENAAAFAAHMAPT | |
| SCHEMBL39726 | 0.70 | MAPT (0.49) | PRKDCKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27645807 | 0.69 | TNKS (0.52) | TNKSKDM4ENAAAFAAHMAPT | |
| Hydrochloric Acid SCHEMBL30765001 | 0.69 | TNKS (0.52) | TNKSKDM4ENAAAFAAHMAPT | |
| SCHEMBL13402978 | 0.69 | ALDH1A1 (0.35) | TNKSKDM4EIDH1NAAAMAPT | |
| SCHEMBL39566 | 0.69 | CNR1 (0.34) | PRKDCMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL138181 | 0.67 | KEAP1 (0.44) | TNKSPRKDCKDM4ENAAAFAAH | |
| SCHEMBL10764104 | 0.67 | KMT2A (0.34) | KDM4EMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL29557633 | 0.67 | KEAP1 (0.44) | TNKSPRKDCKDM4ENAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | claimed |
| JP-9194482-A | — | — | None | — | — | JP | disclosed |
| EP-3682947-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18 | GB006, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3243821-B1 | PHARMACEUTICAL FORMULATIONS FOR REGULATING INTEGRIN CD11B/CD18 | GB006 INC (US) | 2020-02-26 | — | — | EP | disclosed |
| CN-106038558-B | Compounds and methods for modulating integrin CD11b/CD18 | GB006公司 | 2020-01-10 | — | — | CN | disclosed |
| EP-3243821-A1 | PHARMACEUTICAL FORMULATIONS FOR REGULATING INTEGRIN CD11B/CD18 | Adhaere Pharamaceuticals, Inc. (US) | 2017-11-15 | — | — | EP | disclosed |
| CN-106038558-A | Compounds and methods for regulating integrin CD11B/CD18 | 阿德黑雷制药公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103189500-B | Compounds and methods for modulating integrin CD11b/CD18 | 阿德黑雷制药公司 | 2016-06-15 | — | — | CN | disclosed |
| EP-2591092-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18 | Adhaere Pharamaceuticals, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012005800-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18 | ADHAERE PHARAMACEUTICALS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |
| CN-1161968-A | Pyridine condensed thienyl- and furyl-oxazolidinone compounds | BAYER AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| CN-1161968-A | Pyridine condensed thienyl- and furyl-oxazolidinone compounds | BAYER AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| CN-1161968-A | Pyridine condensed thienyl- and furyl-oxazolidinone compounds | BAYER AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| JP-H09194482-A | PYRIDO-CONDENSED THIENYL-AND FURANYL-OXAZOLIDINONES | BAYER AG | 1997-07-29 | — | — | JP | disclosed |
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |