Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 7/20 | 0.40 |
| ▸ | ACE | P12821 | 7/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034324 | 1.00 | PPARG (0.41) | PPARGPPARDPPARAMMEACE | |
| SCHEMBL5407004 | 0.87 | CTRB1 (0.40) | PPARGPPARA | |
| SCHEMBL30510366 | 0.87 | CTRB1 (0.40) | PPARGPPARA | |
| SCHEMBL4600067 | 0.87 | CTRB1 (0.40) | PPARGPPARA | |
| SCHEMBL4600752 | 0.87 | CTRB1 (0.40) | PPARGPPARA | |
| SCHEMBL1405759 | 0.87 | LDHA (0.51) | MMP1MEN1KMT2A | |
| SCHEMBL4600010 | 0.87 | LDHA (0.47) | PPARGPPARAMMP9KMT2A | |
| SCHEMBL30510242 | 0.87 | LDHA (0.47) | PPARGPPARAMMP9KMT2A | |
| SCHEMBL25183036 | 0.86 | RAB9A (0.43) | PPARAMMP9MMP8MMP1MEN1 | |
| SCHEMBL4183822 | 0.86 | PIN1 (0.36) | PPARGPPARAMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018859-A1 | Arylmethylene substituted N-acyl-beta-amino alcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-28 | — | — | EP | disclosed |