SCHEMBL40344

SCHEMBL40344

CCCCOC(=O)CCn1cncc1C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
QPCT Q16769 5/20 0.40
GSK3B P49841 1/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
DGKA P23743 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45904 0.75 ALDH1A1 (0.58) CYP3A4CYP2D6CYP2C9MAPK1ALDH1A1
SCHEMBL17916289 0.73 ALDH1A1 (0.41) MAPK1ALDH1A1GAAMAPTRECQL
SCHEMBL45905 0.71 TBXAS1 (0.54) MAPK1ALDH1A1GAAQPCTLMNA
SCHEMBL8510644 0.70 ALDH1A1 (0.41) CYP2C9MAPK1ALDH1A1GAAMAPT
SCHEMBL5166306 0.69 MAPK1 (0.58) MAPK1ALDH1A1GAAGSK3BMAPT
Dibutylsuccinate SCHEMBL3977806 0.69 DGKA (0.67) MAPK1ALDH1A1MAPTL3MBTL1DGKA
Dibutylsuccinate SCHEMBL50411 0.69 DGKA (0.67) MAPK1ALDH1A1MAPTL3MBTL1DGKA
SCHEMBL28735791 0.68 GAA (0.49) MAPK1ALDH1A1GAAMAPTRECQL
SCHEMBL23880027 0.68 GAA (0.52) MAPK1ALDH1A1GAAMAPTL3MBTL1
SCHEMBL4117806 0.68 DGKA (0.59) ALDH1A1GAAMAPTDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571908-B1 POLYMERIZABLE IONIC LIQUID COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2017-04-26 EP disclosed
US-8383721-B2 Polymerizable ionic liquid compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-26 US disclosed
CN-102906133-A Polymerizable ionic liquid compositions 3M INNOVATIVE PROPERTIES CO 2013-01-30 CN disclosed
US-20110288227-A1 POLYMERIZABLE IONIC LIQUID COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2011-11-24 US disclosed