Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.66 |
| ▸ | RAB9A | P51151 | 12/20 | 0.66 |
| ▸ | MEN1 | O00255 | 11/20 | 0.66 |
| ▸ | NPC1 | O15118 | 9/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 11/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.64 |
| ▸ | RELA | Q04206 | 6/20 | 0.64 |
| ▸ | CASP3 | P42574 | 4/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17943327 | 0.90 | ALOX15 (0.65) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL404975 | 0.89 | KMT2A (0.81) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL10358565 | 0.86 | RAB9A (0.77) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL22415561 | 0.82 | MAPT (0.66) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL21440049 | 0.82 | MAPT (0.62) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL10357444 | 0.81 | MEN1 (0.80) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL16500504 | 0.81 | APP (0.65) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL24897238 | 0.81 | RAB9A (0.56) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL17279800 | 0.81 | RAB9A (0.56) | KMT2ARAB9AMEN1NPC1ALOX15 | |
| SCHEMBL4239940 | 0.81 | MEN1 (0.83) | KMT2ARAB9AMEN1NPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185730-A1 | DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20120065247-A1 | MODULATING IRES-MEDIATED TRANSLATION | DISCOVERYBIOMED, INC. (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185730-A1 | DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES | PARK7, APP, HYPK | KMT2A 4175/4885RAB9A 1574/4885MEN1 1938/4885 |
| US-20120065247-A1 | MODULATING IRES-MEDIATED TRANSLATION | EIF2AK2, EIF4EBP1, EIF4E | KMT2A 2702/4885RAB9A 2106/4885MEN1 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.