Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041186 | 0.93 | CHRM5 (0.45) | F10F2CHRM5CHRM1ADAM17 | |
| SCHEMBL4034722 | 0.88 | F10 (0.46) | F10F2CHRM5CTSSCHRM1 | |
| SCHEMBL1381762 | 0.86 | GAA (0.49) | — | |
| SCHEMBL4032774 | 0.79 | GAA (0.54) | SMN1; SMN2 | |
| SCHEMBL4032585 | 0.78 | MMP1 (0.49) | CHRM1CAPN1 | |
| SCHEMBL4034993 | 0.76 | CACNA2D1 (0.48) | — | |
| SCHEMBL4033974 | 0.74 | MAPT (0.47) | SMN1; SMN2 | |
| SCHEMBL4034091 | 0.73 | GAA (0.49) | CHRM5CHRM1SMN1; SMN2 | |
| SCHEMBL4034484 | 0.72 | MMP1 (0.44) | CHRM1CAPN1 | |
| SCHEMBL4032376 | 0.71 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |