Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034513 | 0.88 | F10 (0.44) | F10F2ADAM17CHRM5CTSS | |
| SCHEMBL4033974 | 0.87 | MAPT (0.47) | LMNATP53 | |
| SCHEMBL4036877 | 0.84 | ALDH1A1 (0.52) | POLBLMNATP53CHRM5 | |
| SCHEMBL4033586 | 0.83 | ALDH1A1 (0.55) | POLBLMNA | |
| SCHEMBL4035740 | 0.81 | ALDH1A1 (0.51) | POLBLMNA | |
| SCHEMBL4041186 | 0.81 | CHRM5 (0.45) | F10F2ADAM17CHRM5ATM | |
| SCHEMBL4039378 | 0.80 | MMP1 (0.52) | POLBLMNA | |
| SCHEMBL4035627 | 0.79 | ALDH1A1 (0.48) | POLBLMNA | |
| SCHEMBL4035716 | 0.79 | ALDH1A1 (0.46) | POLBLMNATP53 | |
| SCHEMBL4032869 | 0.77 | POLB (0.46) | POLBLMNAADAM17TP53ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |