⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833548 | 0.66 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL7447299 | 0.66 | — | — | |
| SCHEMBL103011 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL6609504 | 0.64 | — | — | |
| SCHEMBL6237482 | 0.64 | — | — | |
| SCHEMBL3389545 | 0.62 | NOS1 (0.46) | — | |
| SCHEMBL7416327 | 0.61 | ADORA2B (0.32) | — | |
| SCHEMBL4800293 | 0.60 | — | — | |
| SCHEMBL9832254 | 0.59 | — | — | |
| SCHEMBL17675545 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355646-B1 | MUSCARINIC RECEPTOR AGONISTS | UNIV TOLEDO (US) | 2009-05-13 | — | — | EP | disclosed |
| US-6602891-B2 | Muscarinic receptor agonists | THE UNIVERSITY OF TOLEDO | 2003-08-05 | — | — | US | disclosed |
| US-20030032658-A1 | Muscarinic receptor agonists | MESSER WILLIAM S (US) | 2003-02-13 | — | — | US | disclosed |
| US-6376675-B2 | PYRIDYL-1,2,5-THIADIAZOLE DERIVATIVES | THE UNIVERSITY OF TOLEDO | 2002-04-23 | — | — | US | disclosed |
| US-6369081-B1 | Muscarinic receptor agonists | THE UNIVERSITY OF TOLEDO | 2002-04-09 | — | — | US | disclosed |
| US-20010036953-A1 | Pyridyl-1,2,5-thiadiazole derivatives | TOLEDO, THE UNIVERSITY OF | 2001-11-01 | — | — | US | disclosed |
| US-6211204-B1 | THIADIAZOLE, HYDROGENATED PYRIDINE DERIVATIVES | UNIVERSITY OF TOLEDO | 2001-04-03 | — | — | US | disclosed |
| US-6096767-A | Muscarinic receptor agonists | THE UNIVERSITY OF TOLEDO (US) | 2000-08-01 | — | — | US | disclosed |