SCHEMBL4035124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4036670	0.93	CRHR1 (0.41)	SPRCRHR1MMP3MMP12
	SCHEMBL4033668	0.85	HDAC1 (0.37)	CRHR1HTR1ADRD2DRD4DRD3
	SCHEMBL4032827	0.82	CRHR1 (0.42)	CRHR1
	SCHEMBL4038331	0.80	CRHR1 (0.42)	CRHR1MMP3MMP12
	SCHEMBL4032505	0.78	CRHR1 (0.43)	CRHR1CNR2MMP3MMP12
	SCHEMBL5847449	0.76	CRHR1 (0.47)	CRHR1
	SCHEMBL4032861	0.75	CRHR1 (0.66)	CRHR1
	SCHEMBL5848998	0.75	HTT (0.39)	HTR1ADRD2DRD4DRD3MMP3
	SCHEMBL5847945	0.74	CRHR1 (0.47)	CRHR1HTR1ADRD2DRD4DRD3
	SCHEMBL5847816	0.73	DRD2 (0.42)	CRHR1HTR1ADRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.