Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP2 | O95551 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | S100A4 | P26447 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423947 | 0.70 | CDC25B (0.54) | LMNATDP2ALDH1A1MAPTHTT | |
| SCHEMBL6481220 | 0.70 | CDC25B (0.54) | LMNATDP2ALDH1A1MAPTHTT | |
| SCHEMBL6793063 | 0.67 | MEN1 (0.33) | LMNAKMT2AMEN1 | |
| Anthraquinone SCHEMBL8517968 | 0.66 | KMT2A (0.57) | CASP3LMNATDP2ALDH1A1MAPT | |
| SCHEMBL4784115 | 0.66 | PTPRC (0.50) | LMNAALDH1A1MAPTS100A4NSD2 | |
| SCHEMBL8942748 | 0.65 | CASP3 (0.48) | CASP3LMNATDP2ALDH1A1MAPT | |
| SCHEMBL8423601 | 0.64 | AKT1 (0.47) | LMNAALDH1A1MAPTALOX15KMT2A | |
| SCHEMBL5056798 | 0.63 | CYP2C19 (0.46) | LMNAALDH1A1MAPTHTTPKM | |
| Anthraquinone SCHEMBL10663875 | 0.63 | PTPRC (0.56) | CASP3LMNATDP2ALDH1A1MAPT | |
| Anthraquinone SCHEMBL11789994 | 0.63 | KMT2A (0.56) | CASP3LMNATDP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673354-B1 | ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | ORTHO MCNEIL PHARM INC (US) | 2009-04-22 | — | — | EP | disclosed |