Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 3/20 | 0.46 |
| ▸ | TDP2 | O95551 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | GALK1 | P51570 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939989 | 0.86 | APAF1 (0.54) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL14894567 | 0.86 | MAPT (0.52) | CASP3CDC25BMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10952694 | 0.86 | HTT (0.54) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL11647582 | 0.82 | KMT2A (0.40) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL10493719 | 0.82 | CASP3 (0.39) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL11616539 | 0.78 | MAPT (0.50) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL3186176 | 0.77 | CYP3A4 (0.35) | POLBCYP3A4 | |
| SCHEMBL11412142 | 0.77 | GABRA1 (0.46) | CASP3KMT2AMEN1CDC25BMAPT | |
| SCHEMBL9444224 | 0.76 | PTPN1 (0.51) | CASP3KMT2AMEN1MAPTKDM4E | |
| SCHEMBL23960003 | 0.75 | MAOA (0.47) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545391-A | Removal of hydrogen sulphide | SOLVAY INTEROX LIMITED (GB) | 1996-08-13 | — | — | US | claimed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | CCNK, CDK3, CCNO | CASP3 940/4885KMT2A 1803/4885MEN1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.