Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.54 |
| ▸ | CDC25A | P30304 | 5/20 | 0.54 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.54 |
| ▸ | S100A4 | P26447 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TDP2 | O95551 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481220 | 1.00 | CDC25B (0.54) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL3997199 | 0.76 | PGR (0.37) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL12220363 | 0.75 | CDC25B (0.55) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| Anthraquinone SCHEMBL11302120 | 0.73 | CDC25B (0.80) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL23790255 | 0.73 | TDP2 (0.64) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL8289268 | 0.72 | MAOA (0.33) | CDC25BCDC25AMAP2K7MAPTLMNA | |
| Anthraquinone SCHEMBL11696823 | 0.71 | MEN1 (0.75) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL4036050 | 0.70 | CASP3 (0.41) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| SCHEMBL1287111 | 0.70 | CDC25B (1.00) | CDC25BCDC25AMAP2K7S100A4MAPT | |
| Anthraquinone SCHEMBL5958714 | 0.70 | CDC25B (0.86) | CDC25BCDC25AMAP2K7S100A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182305-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | Iowa State University Research Foundation, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |