Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034864 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBHTTGAAPKM | |
| SCHEMBL6190434 | 0.79 | GAA (0.48) | ALDH1A1POLBHTTGAAPKM | |
| SCHEMBL4032820 | 0.72 | GAA (0.49) | ALDH1A1GAAMMP1MMP9MMP13 | |
| SCHEMBL4034991 | 0.71 | GHSR (0.48) | MMP1MMP9MMP13 | |
| SCHEMBL2707026 | 0.69 | MMP1 (0.59) | ALDH1A1POLBHTTGAAUSP2 | |
| SCHEMBL5244514 | 0.69 | ALDH1A1 (0.72) | ALDH1A1POLBHTTGAAPKM | |
| SCHEMBL4033382 | 0.69 | POLB (0.43) | ALDH1A1POLBHTTGAAPKM | |
| SCHEMBL9517197 | 0.68 | ALDH1A1 (0.56) | ALDH1A1POLBGAAKMT2ASMO | |
| SCHEMBL6228643 | 0.66 | OPRM1 (0.43) | ALDH1A1HTTSMO | |
| SCHEMBL4033401 | 0.65 | MMP1 (0.54) | ALDH1A1POLBHTTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | disclosed |