Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adenine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL27690901 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL27773964 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL6388001 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8426316 | 0.98 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL5663794 | 0.95 | CYP1A2 (0.43) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL10790458 | 0.89 | NOTUM (0.34) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL18260155 | 0.89 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL385841 | 0.88 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3416954 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8110 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2418 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121286350-B | Cultivation method for tissue culture, rapid propagation and seedling culture of asparagus | 江西省农业科学院蔬菜花卉研究所 | 2026-05-19 | — | — | CN | claimed |
| US-20260107894-A1 | METHOD FOR HIGH-EFFICIENCY REGENERATION OF POTATO PROTOPLAST | INNER MONGOLIA UNIVERSITY (CN) | 2026-04-23 | — | — | US | claimed |
| US-20260098243-A1 | DURA MATER-DERIVED STEM CELLS AND METHOD FOR PRODUCING THE SAME | CATHOLIC UNIV KOREA IND ACADEMIC COOPERATION FOUNDATION (KR) | 2026-04-09 | — | — | US | claimed |
| CN-121575022-A | Saccharomyces cerevisiae engineering bacteria for efficiently producing 2' -fucosyllactose, construction method and application thereof | 山东大学 | 2026-02-27 | — | — | CN | claimed |
| CN-119866942-A | Regeneration breeding method of hydrangea plant | 中国农业科学院蔬菜花卉研究所 | 2025-04-25 | — | — | CN | claimed |
| CN-119799735-A | Fungal laccase over-expression gene, plasmid, bacterial strain and laccase expression method | 安徽大学 | 2025-04-11 | — | — | CN | claimed |
| CN-119699192-A | Method for inducing regeneration plants based on small cobs of green-stalk bamboos | 西南林业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119367232-A | Skin care composition and preparation method and application thereof | 山东云景生物科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-118901587-B | Efficient regeneration method of potato protoplasm | 内蒙古大学 | 2025-01-28 | — | — | CN | claimed |
| CN-118901587-A | Efficient regeneration method of potato protoplasm | 内蒙古大学 | 2024-11-08 | — | — | CN | claimed |
| EP-0672162-A4 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF -i(TAXUS) SPECIES. | PHYTON CATALYTIC INC (US) | 1995-11-29 | — | — | EP | claimed |
| EP-0672162-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON CATALYTIC, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| CN-1099558-A | Phytohormone combination method and phytohormone thereof | ZHANG JIANMIN (CN) | 1995-03-08 | — | — | CN | claimed |
| WO-1993017121-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON CATALYTIC, INC. (US) | 1993-09-02 | — | — | WO | claimed |
| US-5030572-A | Cutting cotyledon tissue of nongerminated embryo; culturing ex plant on medium of 1-naphthaleneacetic acid or indole-3-acetic acid, benzyladenine, basal mineral salts containing potassium nitrate, carbohydrate; rooting; growing | LUBRIZOL GENETICS, INC. (US) | 1991-07-09 | — | — | US | claimed |
| US-4687743-A | Sunflower regeneration media, method of use and plants regenerated thereon | STAUFFER CHEMICAL COMPANY (US) | 1987-08-18 | — | — | US | claimed |
| US-4684612-A | Process for regenerating soybeans | SUNGENE TECHNOLOGIES CORPORATION (US) | 1987-08-04 | — | — | US | claimed |
| US-4681849-A | REGENERATION OF SUNFLOWER PLANTS FROM CULTURED SUNFLOWER TISSUE | STAUFFER CHEMICAL COMPANY (US) | 1987-07-21 | — | — | US | claimed |
| EP-0171679-A1 | Process for regenerating soybeans | SUNGENE TECHNOLOGIES CORPORATION (US) | 1986-02-19 | — | — | EP | claimed |
| US-4038778-A | CRUCIFERAE, INDOLEACETIC ACID, KINETIN, ADENINE SULFATE | GTE LABORATORIES INCORPORATED (US) | 1977-08-02 | — | — | US | claimed |