Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4042073 | 0.90 | SIGMAR1 (0.39) | OPRM1OPRL1TNKSSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL4042152 | 0.88 | OPRM1 (0.46) | OPRM1OPRL1TNKSSIGMAR1DRD2 | |
| SCHEMBL5112591 | 0.86 | OPRM1 (0.38) | OPRM1OPRL1TNKSSIGMAR1DRD2 | |
| SCHEMBL4035221 | 0.85 | OPRM1 (0.36) | OPRM1OPRL1TNKSSIGMAR1DRD2 | |
| SCHEMBL7654525 | 0.75 | SIGMAR1 (0.40) | OPRM1OPRL1SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL7445552 | 0.74 | TNKS (0.43) | TNKSNOTUMHTR2CHTR2BHTR2A | |
| SCHEMBL3973155 | 0.72 | SIGMAR1 (0.38) | OPRM1OPRL1SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL29079061 | 0.65 | MEN1 (0.42) | OPRM1OPRL1TNKSNOTUM | |
| SCHEMBL10063517 | 0.65 | OPRL1 (0.41) | OPRM1OPRL1TNKSHTR2CHTR2B | |
| SCHEMBL171980 | 0.65 | SIGMAR1 (0.54) | TNKSSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528200-B2 | Epoxy hardener systems based on aminobis(methylene-ethyleneurea) | ARDES ENTERPRISES, INC. (US) | 2009-05-05 | — | — | US | claimed |
| US-20070179257-A1 | Epoxy hardener systems based on aminomethylene-ethyleneureas | ARDES ENTERPRISES, INC. | 2007-08-02 | — | — | US | claimed |
| CN-109912530-A | A kind of preparation method than his raw material impurity of department | 上海奥博生物医药技术有限公司 | 2019-06-21 | — | — | CN | disclosed |
| US-7528200-B2 | Epoxy hardener systems based on aminobis(methylene-ethyleneurea) | ARDES ENTERPRISES, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| EP-2051712-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmceuticals Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021375-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20070179257-A1 | Epoxy hardener systems based on aminomethylene-ethyleneureas | ARDES ENTERPRISES, INC. | 2007-08-02 | — | — | US | disclosed |