Sugi Predict

Sugi Predict / Compounds / SCHEMBL4037801

SCHEMBL4037801

SCHEMBL4037801

O=C(O)c1ccc(F)c(B(O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ TTR P02766 4/20 0.43
▸ ERN1 O75460 1/20 0.42
▸ TSHR P16473 3/20 0.42
▸ TP53 P04637 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ CA1 P00915 3/20 0.42
▸ CA2 P00918 3/20 0.42
▸ CA12 O43570 2/20 0.42
▸ CA4 P22748 2/20 0.42
▸ CA6 P23280 2/20 0.42
▸ CA7 P43166 2/20 0.42
▸ CA9 Q16790 2/20 0.42
▸ CA14 Q9ULX7 2/20 0.42
▸ GAA P10253 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31224923 1.00 LMNA (0.50) LMNAMAPK1HTTRAB9ATTR
SCHEMBL29547008 0.84 LMNA (0.55) LMNAMAPK1HTTRAB9ATTR
SCHEMBL1289685 0.84 LMNA (0.55) LMNAMAPK1HTTRAB9ATTR
SCHEMBL841590 0.84 CES2 (0.42) LMNARAB9AMAPTL3MBTL1CES2
SCHEMBL973928 0.82 PARP1 (0.50) TTRERN1TSHRKDM4ECA1
SCHEMBL6522758 0.79 ERN1 (0.50) ERN1POLBCES2CES1KMT2A
SCHEMBL3995737 0.79 HDAC6 (0.46) HTTTSHRCA2GAASMN1; SMN2
SCHEMBL29919394 0.79 HDAC6 (0.46) HTTTSHRCA2GAASMN1; SMN2
SCHEMBL701513 0.79 CA1 (0.50) LMNAMAPK1HTTRAB9AERN1
SCHEMBL29626852 0.79 CA1 (0.50) LMNAMAPK1HTTRAB9AERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025231161-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-11-06 — — WO claimed
US-20250332181-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-10-30 — — US claimed
CN-119735600-A 3-Ureido substituted thieno [2,3-b ] pyridine compound and preparation method and application thereof 华东师范大学 2025-04-01 — — CN claimed
CN-113634240-B Fluorescent magnetic composite nanofiber, preparation method and application thereof 宏葵生物（中国）股份有限公司 2023-10-27 — — CN claimed
CN-116712599-A High-tensile wound-healing-promoting antibacterial hydrogel dressing, preparation method and application 江南大学附属医院 2023-09-08 — — CN claimed
CN-113697808-B Transition metal oxide-loaded porous carbon material, and preparation method and application thereof 山东交通学院 2022-11-18 — — CN claimed
CN-111424429-B Metal sulfide porous framework material, and preparation method and application thereof 山东交通学院 2022-09-23 — — CN claimed
CN-114805856-A Injectable pH/ROS dual-response hydrogel and preparation method and application thereof 天津大学 2022-07-29 — — CN claimed
CN-113697808-A Transition metal oxide-loaded porous carbon material, and preparation method and application thereof 山东交通学院 2021-11-26 — — CN claimed
CN-113634240-A Fluorescent magnetic composite nanofiber, and preparation method and application thereof 山东交通学院 2021-11-12 — — CN claimed
CN-111146496-B Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池股份有限公司 2021-07-13 — — CN claimed
CN-112679535-A Small molecule PAD4 inhibitor and preparation method and application thereof 首都医科大学 2021-04-20 — — CN claimed
CN-111424429-A Metal sulfide porous framework material, and preparation method and application thereof 山东交通学院 2020-07-17 — — CN claimed
CN-111162313-A Polymer electrolyte and lithium ion battery 珠海冠宇电池有限公司 2020-05-15 — — CN claimed
CN-111146496-A Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池有限公司 2020-05-12 — — CN claimed
US-12637436-B2 Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2026-05-26 — — US disclosed
US-20260060250-A1 HERBICIDAL PYRIDONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-03-05 — — US disclosed
US-20050245513-A1 Hetero-bridge substituted 8-arylquinoline pde4 inhibitors MERCK FROSST CANADA LTD. (CA) 2005-11-03 — — US disclosed
EP-1487797-A1 HETERO-BRIDGE SUBSTITUTED 8-ARYLQUINOLINE PDE4 INHIBITORS Merck Frosst Canada & Co. (CA) 2004-12-22 — — EP disclosed
WO-2003078397-A1 HETERO-BRIDGE SUBSTITUTED 8-ARYLQUINOLINE PDE4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2003-09-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245513-A1 Hetero-bridge substituted 8-arylquinoline pde4 inhibitors PDE4A, PDE4B, PDE4C LMNA 4124/4885MAPK1 1323/4885HTT 3504/4885
US-20260060250-A1 HERBICIDAL PYRIDONE DERIVATIVES CBR3, CBR1, CYP4B1 LMNA 1347/4885MAPK1 1276/4885HTT 3706/4885
US-20250332181-A1 ANTIBIOTIC METHODS AND COMPOSITIONS CMBL, EBPL, BPGM LMNA 1849/4885MAPK1 4152/4885HTT 4386/4885
US-12637436-B2 Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof GRM3, GRM2, GRM1 LMNA 4245/4885MAPK1 1372/4885HTT 2076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.