Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720308 | 0.85 | HTT (0.41) | FFAR2OPRL1KDM4EMAPTLMNA | |
| SCHEMBL28096957 | 0.83 | MEN1 (0.44) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23292665 | 0.83 | HTT (0.39) | OPRL1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL12082444 | 0.82 | ALDH1A1 (0.41) | NPC1RAB9ACFTRFFAR2PIK3CD | |
| SCHEMBL11693073 | 0.81 | ALDH1A1 (0.47) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15014118 | 0.81 | DDB1 (0.44) | CFTRFFAR2PIK3CDKDM4EMAPT | |
| SCHEMBL25353462 | 0.81 | KDM1A (0.38) | NPC1RAB9ACFTRFFAR2PIK3CD | |
| SCHEMBL15830059 | 0.80 | PRMT5 (0.39) | NPC1RAB9ACFTRPRMT5WDR77 | |
| SCHEMBL25356320 | 0.79 | KDM1A (0.37) | NPC1RAB9ACFTRFFAR2PIK3CD | |
| SCHEMBL19227318 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-1247807-B1 | PROCESSES FOR PRODUCING TETRAHYDROPYRANYL-4-SULFONATE AND 4-AMINOTETRAHYDROPYRAN COMPOUND | UBE INDUSTRIES (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6653489-B2 | Reacting 3-buten-1-ol with a formaldehyde compound and an organic sulfonic acid | UBE INDUSTRIES, INC. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20030004359-A1 | Processes for producing tetrahydropyranyl-4-sulfonates and 4-aminotetrahydropyran compound | UBE INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | US | disclosed |
| EP-1247807-A1 | PROCESSES FOR PRODUCING TETRAHYDROPYRANYL-4-SULFONATE AND 4-AMINOTETRAHYDROPYRAN COMPOUND | Ube Industries, Ltd. (JP) | 2002-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004359-A1 | Processes for producing tetrahydropyranyl-4-sulfonates and 4-aminotetrahydropyran compound | HPD, DHPS, FDPS | NPC1 4583/4885RAB9A 4840/4885CFTR 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.