Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 11/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884188 | 0.77 | QPCT (0.35) | QPCTPIM1PIM2 | |
| SCHEMBL3886296 | 0.76 | EPHX2 (0.39) | QPCT | |
| SCHEMBL3590822 | 0.73 | MEN1 (0.46) | QPCTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3590816 | 0.73 | MEN1 (0.46) | QPCTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3877594 | 0.71 | NAAA (0.42) | QPCT | |
| SCHEMBL3563541 | 0.71 | DRD2 (0.55) | NOTUMMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8361801 | 0.70 | SIGMAR1 (0.45) | KMT2AALOX5 | |
| SCHEMBL13737609 | 0.70 | CYP17A1 (0.58) | QPCTHTTALOX5CCR2 | |
| SCHEMBL9205520 | 0.69 | HTR2C (0.46) | HTT | |
| SCHEMBL3582370 | 0.68 | HTT (0.41) | QPCTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010524-A2 | S1P RECEPTOR MODULATING COMPOUNDS | Epix Delaware, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007109330-A2 | S1P RECEPTOR MODULATING COMPOUNDS | EPIX DELAWARE, INC. (US) | 2007-09-27 | — | — | WO | disclosed |