Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 11/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884188 | 0.86 | QPCT (0.35) | QPCTQPCTLALDH1A1 | |
| SCHEMBL3879388 | 0.82 | EPHX2 (0.39) | EPHX2NAAAACACBALDH1A1PTGER2 | |
| SCHEMBL4037907 | 0.76 | QPCT (0.43) | QPCT | |
| SCHEMBL8573927 | 0.74 | RXRA (0.36) | EPHX2QPCTQPCTLPTGER2PTGER3 | |
| SCHEMBL8575601 | 0.74 | HRH3 (0.36) | EPHX2QPCTQPCTLPTGER2 | |
| SCHEMBL3550353 | 0.70 | DRD2 (0.50) | EPHX2 | |
| SCHEMBL113722 | 0.69 | EPHX2 (0.61) | EPHX2 | |
| SCHEMBL8576418 | 0.68 | FFAR1 (0.38) | EPHX2QPCTQPCTL | |
| SCHEMBL8571822 | 0.68 | PPARD (0.38) | QPCTQPCTL | |
| SCHEMBL8572786 | 0.68 | QPCT (0.38) | QPCTQPCTLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010524-A2 | S1P RECEPTOR MODULATING COMPOUNDS | Epix Delaware, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007109330-A2 | S1P RECEPTOR MODULATING COMPOUNDS | EPIX DELAWARE, INC. (US) | 2007-09-27 | — | — | WO | disclosed |