Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754108 | 0.81 | CHRM2 (0.41) | KMT2AALDH1A1POLBL3MBTL1CHRM2 | |
| SCHEMBL4815974 | 0.80 | MT-CO2 (0.33) | MT-CO2 | |
| SCHEMBL4595993 | 0.79 | CTSD (0.32) | MT-CO2 | |
| SCHEMBL6295798 | 0.78 | MLYCD (0.48) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL219603 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13747089 | 0.78 | MT-CO2 (0.34) | MT-CO2 | |
| SCHEMBL2578067 | 0.78 | CA14 (0.33) | MT-CO2 | |
| SCHEMBL17974957 | 0.77 | MEN1 (0.47) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6215588 | 0.77 | KMT2A (0.43) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10456359 | 0.76 | CHRM2 (0.37) | SMN1; SMN2MEN1CYP2C19KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343807-B1 | DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS | SCHERING CORP (US) | 2009-04-29 | — | — | EP | disclosed |
| US-6911428-B2 | Viricides | SCHERING CORPORATION (US) | 2005-06-28 | — | — | US | disclosed |
| EP-1343807-A2 | DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS | SCHERING CORPORATION (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020147139-A1 | Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2002-10-10 | — | — | US | disclosed |
| WO-2002048172-A2 | DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS | SCHERING CORPORATION (US) | 2002-06-20 | — | — | WO | disclosed |
| EP-0099747-B1 | C-23-MODIFIED DERIVATIVES OF 5-0-MYCAMINOSYL TYLONOLIDE | ELI LILLY AND COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147139-A1 | Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus | PRSS1, PEPD, TMPRSS11D | SMN1; SMN2 4194/4885MEN1 3347/4885CYP3A4 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.