Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038511 | 0.71 | HSD11B1 (0.43) | DRD4 | |
| SCHEMBL19561830 | 0.67 | ALDH1A1 (0.73) | KMT2AMAPTHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL2118205 | 0.67 | ADRB1 (0.80) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL8984615 | 0.64 | SLC6A9 (0.46) | MEN1KMT2AGFERROCK2PRKG1 | |
| SCHEMBL12526583 | 0.64 | CASR (0.45) | MEN1KMT2AGFERTRPM8MAPT | |
| SCHEMBL10323060 | 0.64 | MTNR1A (0.55) | MEN1KMT2AGFERMTNR1BSLC6A9 | |
| SCHEMBL10323057 | 0.64 | MTNR1A (0.55) | MEN1KMT2AGFERMTNR1BSLC6A9 | |
| SCHEMBL3465390 | 0.63 | ADRB1 (0.50) | MEN1KMT2AMTNR1BDRD4MAPT | |
| SCHEMBL9594359 | 0.63 | SPHK1 (0.52) | MEN1KMT2AGFERMTNR1BMAPT | |
| SCHEMBL8690417 | 0.63 | KMT2A (0.62) | MEN1KMT2AGFERROCK2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |