Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | ESRRB | O95718 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESRRA | P11474 | 1/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63633 | 0.99 | MAPT (0.65) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL5573222 | 0.89 | MAPT (0.76) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL24891887 | 0.88 | MAPT (0.64) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL1481563 | 0.87 | GPR119 (0.78) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL2945397 | 0.87 | GPR119 (0.81) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL8354642 | 0.86 | GPR119 (0.62) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL8348627 | 0.86 | GPR119 (0.62) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL13218466 | 0.86 | GPR119 (0.79) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL2453801 | 0.86 | MAPT (0.64) | MAPTLMNAALDH1A1GPR119KMT2A | |
| SCHEMBL26054723 | 0.86 | MAPT (0.64) | MAPTLMNAALDH1A1GPR119KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | MAPT 3367/4885LMNA 3686/4885ALDH1A1 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.