SCHEMBL4038712

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4042556	0.87	LARS1 (0.34)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4042560	0.87	LARS1 (0.34)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4224247	0.84	CTSK (0.41)	MEN1MAPTKMT2ANPSR1ALDH1A1
	SCHEMBL4042041	0.84	CTSK (0.43)	CTSKCTSLCTSSCTSB
	SCHEMBL28694679	0.84	ABCB1 (0.41)	MEN1KMT2APSEN1PSEN2APH1B
	SCHEMBL4355987	0.83	MAPT (0.42)	MEN1MAPTKMT2ANPSR1ALDH1A1
	SCHEMBL4224431	0.82	MAPT (0.41)	MEN1MAPTKMT2ANPSR1ALDH1A1
	SCHEMBL4040862	0.82	L3MBTL1 (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4040856	0.82	L3MBTL1 (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4043968	0.80	PSEN1 (0.44)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.