Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036344 | 0.88 | SMPD3 (0.41) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4034103 | 0.81 | SMPD3 (0.40) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4042076 | 0.80 | MAPT (0.39) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4034089 | 0.80 | SMPD3 (0.46) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4042546 | 0.80 | MAPT (0.43) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4034301 | 0.80 | GABRA1 (0.41) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4040171 | 0.79 | TUBB4A (0.41) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL15225671 | 0.79 | SMPD3 (0.40) | SMPD3MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4036732 | 0.79 | PDE5A (0.41) | MAPTTSHRSMN1; SMN2EGFRFGFR1 | |
| SCHEMBL4039716 | 0.79 | ERN1 (0.43) | SMPD3MAPTTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | TUBB1, TUBA1C, TUBB6 | SMPD3 3149/4885MAPT 45/4885TUBB4A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.