Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 12/20 | 0.41 |
| ▸ | GABRD | O14764 | 12/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.41 |
| ▸ | GABRE | P78334 | 12/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14209955 | 0.91 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4854540 | 0.90 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5217113 | 0.85 | GABRB3 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14208660 | 0.84 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055762 | 0.82 | GABRB3 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7669983 | 0.82 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3370802 | 0.81 | GABRB3 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL712966 | 0.81 | GABRB3 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2001797 | 0.80 | GABRB3 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6623244 | 0.79 | GABRB3 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-2104428-B1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER IP GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20130045996-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-20130045996-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-20130012562-A1 | Composition for Controlling Parasites on Animals | BAYER ANIMAL HEALTH GMBH (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| EP-0976737-B1 | PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | NIHON NOHYAKU CO LTD (JP) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008080542-A2 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008080541-A1 | AGENTS FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| US-7371768-B2 | Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-6335357-B1 | 1-ARYL-3-CYANO-5-(HET)ARYLALKYLAMINOPYRAZOLE DERIVATIVES; INSECTICIDES FOR AGRICULTURE AND HORTICULTURE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-0976737-A1 | PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007611-A1 | Combination product for controlling parasites on animals | CYCS, CYP3A43, CDIPT | GABRP 68/4885GABRD 346/4885GABRA1 385/4885 |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | CYCS, CYP3A43, CDIPT | GABRP 68/4885GABRD 346/4885GABRA1 385/4885 |
| US-20130045996-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | CYCS, CYP3A43, CDIPT | GABRP 68/4885GABRD 346/4885GABRA1 385/4885 |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | CYCS, PTMS, PLCB3 | GABRP 687/4885GABRD 3073/4885GABRA1 2122/4885 |
| US-20130012562-A1 | Composition for Controlling Parasites on Animals | CYCS, PTMS, PLCB3 | GABRP 687/4885GABRD 3073/4885GABRA1 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.