Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 8/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MPI | P34949 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653681 | 0.81 | DRD2 (0.58) | MAPTLMNAKMT2AMAPK1USP2 | |
| SCHEMBL4039345 | 0.80 | HTT (0.46) | MAPTKDM4ELMNATDP1SMN1; SMN2 | |
| SCHEMBL11955292 | 0.78 | METAP2 (0.88) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL28462402 | 0.78 | KDM4E (0.59) | MAPTKDM4ELMNATDP1SMN1; SMN2 | |
| SCHEMBL31452761 | 0.76 | METAP2 (0.97) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL9996355 | 0.75 | METAP2 (1.00) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL10415547 | 0.74 | MAPT (0.66) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL10414290 | 0.74 | CDK1 (0.67) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL13391489 | 0.74 | MAPT (1.00) | METAP2MAPTKDM4ELMNATDP1 | |
| SCHEMBL2014459 | 0.74 | CDK1 (0.62) | METAP2MAPTKDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |