Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.46 |
| ▸ | PPARA | Q07869 | 12/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484278 | 0.85 | PPARG (0.39) | PPARGPPARAMAPTMTNR1AMTNR1B | |
| SCHEMBL4035957 | 0.84 | PPARG (0.48) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL9911068 | 0.79 | PPARG (0.55) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL4033955 | 0.78 | MAP4K4 (0.54) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL4040746 | 0.78 | PPARG (0.55) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL13049316 | 0.77 | LMNA (0.60) | MEN1CYP3A4MAPTKMT2AMTNR1A | |
| SCHEMBL11399949 | 0.76 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL1045831 | 0.75 | PPARA (0.69) | PPARGPPARACYP2C19MEN1CYP1A2 | |
| SCHEMBL4037839 | 0.75 | PPARG (0.44) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL3845579 | 0.74 | PPARG (0.56) | PPARGPPARAPTPN7DUSP3PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |