Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484748 | 0.87 | PTGDR2 (0.37) | PPARGPPARAMMP2MMP9MMP12 | |
| SCHEMBL4033120 | 0.86 | MMP2 (0.49) | PPARGPPARAMMP2MMP9MMP12 | |
| SCHEMBL4035957 | 0.81 | PPARG (0.48) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL4040101 | 0.77 | PPARA (0.48) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL4039835 | 0.75 | PPARG (0.46) | PPARGPPARAPTPN7DUSP3PTPN12 | |
| SCHEMBL3484606 | 0.74 | MMP2 (0.44) | PPARGPPARAMMP2MMP9MMP12 | |
| SCHEMBL6932107 | 0.72 | MMP2 (0.70) | MMP2MMP9MMP12SMN1; SMN2PTGDR2 | |
| SCHEMBL3484527 | 0.71 | CHRNA7 (0.53) | SMN1; SMN2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL9152799 | 0.70 | CYP2C9 (0.57) | MMP2MMP9MMP12SMN1; SMN2PTGDR2 | |
| SCHEMBL4035511 | 0.69 | PPARG (0.49) | PPARGPPARAPTPN7DUSP3PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |