Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795435 | 0.81 | LDHA (0.65) | LDHASLC6A4ACACBALDH1A1PPARG | |
| SCHEMBL4043564 | 0.80 | MAOA (0.47) | ALDH1A1PPARACYP2D6CYP2C19HTT | |
| SCHEMBL4039591 | 0.80 | SLC6A2 (0.47) | SLC6A4ACACBPPARGPPARAFPR2 | |
| SCHEMBL23051836 | 0.80 | LDHA (0.62) | LDHASLC6A4ACACBALDH1A1PPARG | |
| SCHEMBL663059 | 0.80 | LDHA (0.73) | LDHASLC6A4ACACBPPARGPPARA | |
| SCHEMBL3832306 | 0.80 | LDHA (0.62) | LDHASLC6A4ACACBALDH1A1PPARG | |
| SCHEMBL8283100 | 0.80 | LDHA (0.73) | LDHASLC6A4ACACBPPARGPPARA | |
| SCHEMBL10823754 | 0.78 | LDHA (0.61) | LDHASLC6A4ACACBALDH1A1PPARG | |
| SCHEMBL933857 | 0.78 | LDHA (0.61) | LDHASLC6A4ACACBALDH1A1PPARG | |
| SCHEMBL13623718 | 0.78 | LDHA (0.61) | LDHASLC6A4ACACBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038279-A2 | SUBSTITUTED PYRAZOLO [1,5- ALPHA] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | Avigen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007146087-A2 | SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | AVIGEN, INC. (US) | 2007-12-21 | — | — | WO | disclosed |