Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043564 | 0.83 | MAOA (0.47) | PPARAKMT2AMAOB | |
| SCHEMBL4040112 | 0.80 | LDHA (0.56) | ACACBPPARGPPARASLC6A4POLB | |
| SCHEMBL11145872 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL13235901 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL4666674 | 0.78 | PPARG (0.54) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL2555902 | 0.78 | PPARG (0.54) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL4666677 | 0.78 | PPARG (0.54) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL11242882 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL9875052 | 0.77 | SLC6A2 (0.52) | SLC6A2SLC6A3ACACBPPARGPPARA | |
| SCHEMBL27343062 | 0.75 | SLC6A2 (0.50) | SLC6A2SLC6A3ACACBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038279-A2 | SUBSTITUTED PYRAZOLO [1,5- ALPHA] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | Avigen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007146087-A2 | SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | AVIGEN, INC. (US) | 2007-12-21 | — | — | WO | disclosed |