Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572912 | 0.86 | MTNR1A (0.38) | KCNH2 | |
| SCHEMBL3572910 | 0.72 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL13633343 | 0.72 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL14341402 | 0.71 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL5263873 | 0.70 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL13638251 | 0.68 | MTNR1A (0.43) | KCNH2 | |
| SCHEMBL4044878 | 0.68 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL6668585 | 0.68 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL6667268 | 0.67 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL14498826 | 0.67 | KCNH2 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |