Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSV | O60911 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044028 | 0.92 | CTSK (0.50) | CTSKAHRGFERHDAC1TDP1 | |
| SCHEMBL4044537 | 0.90 | CTSK (0.41) | CTSKAHRKDM1AGFERTDP1 | |
| SCHEMBL4043857 | 0.90 | CTSK (0.44) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4040030 | 0.89 | CTSK (0.41) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4048145 | 0.89 | CTSK (0.47) | CTSK | |
| SCHEMBL4040234 | 0.89 | CTSK (0.54) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4041145 | 0.89 | CTSK (0.45) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4040494 | 0.88 | CTSK (0.39) | CTSKAHRKDM1AGFERTDP1 | |
| SCHEMBL4039424 | 0.88 | CTSK (0.41) | CTSKKDM1AGFERTDP1CTSS | |
| SCHEMBL4039055 | 0.88 | CTSK (0.54) | CTSKCTSSCTSVCTSLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1913038-B1 | AMPHOLYTIC COPOLYMER, PRODUCTION THEREOF, AND USE OF THE SAME | BASF SE (DE) | 2013-03-27 | — | — | EP | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1912620-A1 | USE OF ANIONICALLY AND CATIONICALLY AMPHOLYTIC COPOLYMERS | BASF SE (DE) | 2008-04-23 | — | — | EP | claimed |
| EP-1913039-A1 | COPOLYMER CONTAINING SILICONE GROUPS, ITS PREPARATION AND USE | BASF SE (DE) | 2008-04-23 | — | — | EP | claimed |
| WO-2007012610-A1 | COPOLYMER CONTAINING SILICONE GROUPS, ITS PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-01 | — | — | WO | claimed |
| WO-2007010035-A1 | USE OF ANIONICALLY AND CATIONICALLY AMPHOLYTIC COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | WO | claimed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| WO-2009103735-A1 | COMPOSITION CONTAINING AN AMPHOLYTIC COPOLYMER ON THE BASIS OF QUATERNISED MONOMERS CONTAINING NITROGEN AND AT LEAST ONE POLYMER THAT DIFFERS FROM SAID COPOLYMER, AND USE THEREOF | BASF SE (DE) | 2009-08-27 | — | — | WO | disclosed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1913038-A2 | AMPHOLYTIC COPOLYMER, PRODUCTION THEREOF, AND USE OF THE SAME | BASF SE (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1912620-A1 | USE OF ANIONICALLY AND CATIONICALLY AMPHOLYTIC COPOLYMERS | BASF SE (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1761234-A1 | AQUEOUS PREPARATIONS COMPRISING A WATER-SOLUABLE OR WATER-DISPERSIBLE COPOLYMER WHICH CONTAINS AT LEAST ONE MONOMER HAVING A NITROGEN ATOM | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2007010034-A2 | AMPHOLYTIC COPOLYMER, PRODUCTION THEREOF, AND USE OF THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007010035-A1 | USE OF ANIONICALLY AND CATIONICALLY AMPHOLYTIC COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | WO | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
| WO-2005123014-A1 | AQUEOUS PREPARATIONS COMPRISING A WATER-SOLUBLE OR WATER-DISPERSIBLE COPOLYMER WHICH CONTAINS AT LEAST ONE MONOMER HAVING A NITROGEN ATOM | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-29 | — | — | WO | disclosed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | CTSK 2/4885AHR 1859/4885KDM1A 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.