SCHEMBL4040712

SCHEMBL4040712

Cc1ccc(O)c(CN2CCCCC2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.66
GFER P55789 1/20 0.66
CACNA1B Q00975 4/20 0.65
LMNA P02545 1/20 0.64
HPGD P15428 1/20 0.64
ALOX15 P16050 1/20 0.64
ACHE P22303 2/20 0.63
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.50
NR2E3 Q9Y5X4 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
RCE1 Q9Y256 1/20 0.50
GAA P10253 1/20 0.49
CACNB4 O00305 1/20 0.49
CACNA1A O00555 1/20 0.49
CACNA1G O43497 1/20 0.49
CACNG3 O60359 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22425349 0.95 LMNA (0.66) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL2512526 0.91 LMNA (0.74) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL31323214 0.85 LMNA (0.67) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL14423575 0.84 ACHE (0.54) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL12771554 0.84 LMNA (0.48) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL10163424 0.83 ALOX15 (0.65) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL22425608 0.83 LMNA (0.61) TSHRGFERCACNA1BLMNAHPGD
SCHEMBL30596554 0.82 POLB (0.57) CACNA1BHPGDCYP1A2CYP2D6MAPK1
SCHEMBL11821789 0.80 ALDH1A1 (0.54) TSHRGFERCACNA1BHPGDALOX15
SCHEMBL16495328 0.80 TSHR (0.62) TSHRGFERCACNA1BLMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105214-B2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 2006-09-12 US claimed
US-20030124320-A1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION 2003-07-03 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
US-5657064-A Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1997-08-12 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-11820957-B2 Low molecular weight amide/ester containing quaternary ammonium salts THE LUBRIZOL CORPORATION (US) 2023-11-21 US disclosed
EP-3383978-B1 ULTRA-LOW MOLECULAR WEIGHT AMIDE/ESTER CONTAINING QUATERNARY AMMONIUM SALTS HAVING SHORT HYDROCARBON TAILS LUBRIZOL CORP (US) 2023-07-12 EP disclosed
EP-3374440-B1 COATING COMPOSITION COMPRISING QUATERNARY AMINE ADDITIVES AND ITS USE LUBRIZOL CORP (US) 2023-06-21 EP disclosed
CN-111253994-B Low molecular weight amide/ester containing quaternary ammonium salts 路博润公司 2022-10-04 CN disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed