Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904866 | 0.90 | GPR35 (0.40) | GPR35AKR1C3AKR1C2SMN1; SMN2MAPT | |
| SCHEMBL8566031 | 0.76 | SMN1; SMN2 (0.64) | AKR1C3AKR1C2SMN1; SMN2MAOBCFTR | |
| SCHEMBL2907418 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2MAOBMAPTATMALDH1A1 | |
| SCHEMBL7591657 | 0.69 | SMN1; SMN2 (0.75) | GPR35AKR1C3AKR1C2SMN1; SMN2MAPT | |
| SCHEMBL6492271 | 0.68 | SMN1; SMN2 (0.84) | AKR1C3AKR1C2SMN1; SMN2MAOBMAPT | |
| SCHEMBL5696709 | 0.68 | SMN1; SMN2 (0.64) | GPR35AKR1C3AKR1C2SMN1; SMN2MAOB | |
| SCHEMBL4044977 | 0.67 | KDM4E (0.41) | GPR35SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL9683222 | 0.66 | SMN1; SMN2 (0.64) | GPR35AKR1C3AKR1C2SMN1; SMN2MAPT | |
| SCHEMBL9151080 | 0.66 | SMN1; SMN2 (0.64) | AKR1C3AKR1C2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL989189 | 0.66 | SMN1; SMN2 (0.64) | GPR35AKR1C3AKR1C2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | claimed |
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | disclosed |