Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043854 | 0.93 | CTSK (0.39) | CTSKL3MBTL1 | |
| SCHEMBL4040797 | 0.92 | CTSV (0.33) | CTSKL3MBTL1 | |
| SCHEMBL4045411 | 0.90 | PREP (0.33) | PREPFAPCTSKL3MBTL1KDM4E | |
| SCHEMBL4045719 | 0.89 | SMN1; SMN2 (0.32) | CTSKSMN1; SMN2 | |
| SCHEMBL4047816 | 0.86 | CTSK (0.33) | PREPFAPCTSK | |
| SCHEMBL4043247 | 0.85 | CTSK (0.39) | PREPFAPCTSK | |
| SCHEMBL4046418 | 0.84 | CTSK (0.33) | PREPFAPCTSK | |
| SCHEMBL4041133 | 0.84 | CTSK (0.36) | PREPFAPCTSKSMN1; SMN2 | |
| SCHEMBL4042714 | 0.84 | SMN1; SMN2 (0.36) | PREPFAPCTSKTSHRHTT | |
| SCHEMBL4044073 | 0.84 | CTSK (0.33) | PREPFAPCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |