Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.39 |
| ▸ | CTSL | P07711 | 10/20 | 0.33 |
| ▸ | CTSS | P25774 | 8/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040797 | 0.93 | CTSV (0.33) | CTSKCTSLCTSSCTSVL3MBTL1 | |
| SCHEMBL4040960 | 0.93 | PREP (0.32) | CTSKL3MBTL1 | |
| SCHEMBL4043622 | 0.90 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4045719 | 0.90 | SMN1; SMN2 (0.32) | CTSKCTSSCTSB | |
| SCHEMBL4041781 | 0.86 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4048016 | 0.85 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4044439 | 0.84 | CTSK (0.41) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4047763 | 0.84 | CTSK (0.44) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4039790 | 0.84 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4052113 | 0.84 | CTSK (0.41) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |