Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046064 | 0.91 | SMN1; SMN2 (0.35) | SMN1; SMN2CTSKCNR2CTSBCTSS | |
| SCHEMBL4043854 | 0.90 | CTSK (0.39) | CTSKCTSBCTSS | |
| SCHEMBL4040797 | 0.89 | CTSV (0.33) | CTSKCTSS | |
| SCHEMBL4040960 | 0.89 | PREP (0.32) | SMN1; SMN2CTSK | |
| SCHEMBL4047038 | 0.86 | CTSK (0.39) | CTSKCTSBCTSS | |
| SCHEMBL4050728 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2CTSKCTSBCTSS | |
| SCHEMBL4045248 | 0.83 | NPC1 (0.33) | SMN1; SMN2CTSKCTSBCTSS | |
| SCHEMBL4046790 | 0.83 | USP30 (0.36) | CTSKCTSBCTSS | |
| SCHEMBL4041786 | 0.83 | CTSK (0.31) | CTSKCTSBCTSS | |
| SCHEMBL4043593 | 0.83 | USP2 (0.33) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |