Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983648 | 0.87 | LCK (0.57) | FGFR1KDRSRCCYP1A2TSHR | |
| SCHEMBL7983209 | 0.83 | LCK (0.58) | FGFR1KDRSRCALDH1A1HSD17B10 | |
| SCHEMBL7983613 | 0.80 | LCK (0.51) | FGFR1SRCCYP1A2TSHRCYP3A4 | |
| SCHEMBL4041226 | 0.77 | LCK (0.53) | FGFR1KDRSRCCYP1A2TSHR | |
| SCHEMBL7983879 | 0.76 | FGFR1 (0.55) | FGFR1KDRSRCLCKEGFR | |
| SCHEMBL7980015 | 0.76 | LCK (0.52) | FGFR1KDRSRCLCKMAP3K8 | |
| SCHEMBL7983693 | 0.72 | LCK (0.43) | FGFR1KDRSRCLCKEGFR | |
| SCHEMBL7969762 | 0.72 | LCK (0.46) | FGFR1SRCALDH1A1LCK | |
| SCHEMBL4041190 | 0.72 | LCK (0.51) | FGFR1SRCCYP1A2TSHRCYP3A4 | |
| SCHEMBL4041184 | 0.72 | LCK (0.55) | FGFR1KDRSRCCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |